HPE ProLiant, Synergy & Apollo Server Memory Upgrades

233 products

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Server memory matched to HPE systems — All models across the full range, from single-socket edge nodes to Cray HPC nodes.

ProLiant is the bulk of it: DL-series rack servers (DL20, DL110, DL145, DL160, DL320, DL325, DL345, DL360, DL365, DL380, DL385, DL560, DL580), ML-series towers, and BL-series blades, spanning Gen9 through Gen12. Beyond ProLiant: Synergy composable frames, Apollo density systems, Alletra storage, DX SimpliVity nodes, and Cray XD AI and HPC platforms.

Nearly all of it is registered ECC RDIMM (174 listings), with LRDIMM for the highest-capacity builds, and a small run of unbuffered modules for the entry ProLiant boards. Densities from 8GB to 256GB per module, at 2666MHz through 6400MHz.

The split between DDR4 and DDR5 is almost even here — 114 to 104 — because HPE's Gen10 and Gen10 Plus fleets are still very much in production while Gen11 and Gen12 roll out. Generation is the thing to get right: a Gen10 DL380 and a Gen11 DL380 share a model number and take entirely different memory.

Use Shop by System Model to filter to your exact server and generation, or send us the model and Gen and we'll confirm before you order. Lifetime warranty on every module. Purchase orders, net terms and volume pricing for business, government and education buyers.

How to read an HPE memory part number

HPE issues three part numbers for the same physical module. Which one you have depends on whether you are reading a quote, a spare-parts list, or the label on the DIMM. All three cross-reference to the same NEMIX RAM equivalent.

Format	Example	Where you see it
Option kit — ends in -B21	P00922-B21 · P00924-B21 · 815100-B21 · P43328-B21	HPE quotes, configurators, order confirmations, and QuickSpecs. This is the number a reseller sells memory under.
Spare part — ends in -001	P06189-001 · 850881-001 · P11444-001	HPE support parts lists and iLO's memory inventory. The number a field technician orders for a replacement.
Assembly part — ends in -091 (or -0A1 / -H21 on some series)	P03052-091 · 840758-091 · P28223-091	Printed on the module label itself, next to the DRAM maker's part number.

The six-character prefix is the same module across all three suffixes only some of the time — HPE often assigns a different base number to each — so search this page by any one of them, or by the spec on the label (capacity, rank, speed). If you have a quote in -B21 numbers, send us the line items and we return the matched set.

SmartMemory vs Standard Memory

HPE sells two grades. SmartMemory is the registered and load-reduced DIMM line for ProLiant DL, ML, BL, Synergy, and Apollo — the RDIMM and LRDIMM on this page. Standard Memory is the unbuffered ECC UDIMM line for the entry boards: DL20, ML30, MicroServer, and the ML110 in some configurations. They are not interchangeable — a Standard UDIMM will not post in a DL380 and a SmartMemory RDIMM will not post in a MicroServer — and the product titles on this page carry the module type so you can filter by it.

Memory by ProLiant generation

Generation	Servers	Platform	Memory
Gen12	DL360 / DL380 / DL380a Gen12, DL320 / DL340 Gen12, Compute Scale-up, Cray XD	Intel Xeon 6	DDR5-6400 ECC RDIMM · 8 or 12 channels per socket · select models accept MRDIMM-8800
Gen11	DL360 / DL380 / DL560 Gen11, DL320 Gen11, ML350 Gen11, DL325 / DL345 / DL365 / DL385 Gen11, Synergy 480 Gen11, Alletra 4000, SimpliVity 325 / 380 Gen11	4th / 5th Gen Xeon Scalable · EPYC 9004	DDR5-4800 (DDR5-5600 on 5th Gen Xeon refresh) ECC RDIMM · 8 (Intel) or 12 (AMD) channels · no LRDIMM
Gen10 Plus v2	DL360 / DL380 Gen10 Plus, DL325 / DL345 / DL365 / DL385 Gen10 Plus v2, ML350 Gen10 Plus, Apollo 2000 Gen10 Plus	3rd Gen Xeon Scalable · EPYC 7003	DDR4-3200 ECC RDIMM or LRDIMM · 8 channels per socket
Gen10 Plus (AMD)	DL325 / DL385 Gen10 Plus	EPYC 7002	DDR4-3200 ECC RDIMM or LRDIMM · 8 channels per socket
Gen10	DL360 / DL380 / DL560 / DL580 Gen10, DL160 / DL180 Gen10, ML350 Gen10, BL460c Gen10, Synergy 480 / 660 Gen10, Apollo 2000 / 4200 / 6500 Gen10, SimpliVity 380 Gen10	1st / 2nd Gen Xeon Scalable	DDR4-2666 or DDR4-2933 ECC RDIMM or LRDIMM · 6 channels per socket · 2933 requires 2nd Gen Xeon
Gen9	DL360 / DL380 / DL560 / DL580 Gen9, DL160 / DL180 Gen9, ML350 Gen9, BL460c Gen9, Apollo 2000 Gen9	Xeon E5-2600 v3 / v4	DDR4-2133 or DDR4-2400 ECC RDIMM or LRDIMM · 4 channels per socket · 2400 requires v4
Gen8	DL360p / DL380p / DL560 Gen8, ML350p Gen8, BL460c Gen8	Xeon E5-2600 / v2	DDR3-1333 / 1600 / 1866 ECC RDIMM or LRDIMM · 4 channels per socket
Entry / Standard Memory	MicroServer Gen11, DL20 Gen11, ML30 Gen11 · MicroServer Gen10 Plus v2, DL20 Gen10 Plus, ML30 Gen10 Plus · DL20 Gen10, ML30 Gen10	Xeon E-2400 · E-2300 · E-2100 / E-2200	DDR5-4800 ECC UDIMM (Gen11) · DDR4-3200 ECC UDIMM (Gen10 Plus) · DDR4-2666 ECC UDIMM (Gen10) · 2 channels, 4 slots · unbuffered only

Generation lists are representative. The generation is on the front bezel and the chassis label ("Gen10 Plus" and "Gen10 Plus v2" are different platforms), and the installed module's part number is the authority. Use Shop by System Model to filter to your server and generation.

How to find what is installed without downtime

iLO web interface: System Information → Memory. Every slot is listed with capacity, speed, rank, manufacturer, and the HPE part number. The Memory tab also shows the operating speed after POST, so you can see whether 2DPC has stepped it down.
iLO RESTful API / iLOrest: ilorest get Memory returns the same inventory as text, which is convenient for a fleet script.
HPE OneView exports memory inventory across every managed server in one report — the starting point for a multi-node quote.
Intelligent Provisioning (F10 at POST) → System Information shows the same detail on a server without iLO licensing.

Population rules that decide whether it posts

One module type per server. RDIMM and LRDIMM cannot be mixed; entry boards take UDIMM only. If the server is populated with RDIMM, add RDIMM.
Follow the HPE population order. HPE numbers slots per processor and the Setup and Installation Guide gives an explicit order (typically 8 → 10 → 3 → 1 on a 12-slot Gen10 socket). One DIMM per channel first; a lone 64GB module in a 6-channel Gen10 socket runs at one-sixth of available bandwidth.
Balance across processors. HPE BIOS expects symmetric population between CPUs; an unbalanced layout is logged in the IML and can leave one processor without local memory.
Match capacity, speed, and rank within a channel. Mixed speeds run at the slowest module; mixed ranks in a channel can force a lower speed or disable Advanced Memory Protection modes. Identical modules across the server are the safe configuration, which is why we sell matched kits sized to the channel count.
Two DIMMs per channel costs speed. DDR4-2933 typically steps to 2666 at 2DPC on Gen10; DDR4-3200 steps to 2933 on Gen10 Plus; DDR5-4800 steps to 4400 on Gen11. iLO shows the resulting speed.
The CPU sets the ceiling. A Gen10 with a Xeon Silver 4110 runs 2933 modules at 2400. Check the processor's rated memory speed before paying for the faster grade.
Advanced Memory Protection modes need symmetric layout. Advanced ECC is the default. Online Spare, Mirrored Memory, and Fast Fault Tolerance (ADDDC) each have population tables in the server's guide; confirm before enabling on a partial upgrade.

What "compatible equivalent" means here — and what iLO will say

A NEMIX RAM module listed against an HPE part number matches it on every attribute the memory controller checks: DDR generation, capacity, ECC, buffering (registered, load-reduced, or unbuffered), rated speed, rank organization, voltage, and pin count. It is built on DRAM from the same manufacturers HPE sources from and tested in a ProLiant of the target generation before listing. On ProLiant Gen9 and later, POST may display a message that non-HPE-qualified memory is installed and iLO may log an informational event; the server boots, recognizes full capacity, and runs the modules at spec. Some HPE SmartMemory-only features — memory performance telemetry in iLO, and Fast Fault Tolerance on certain models — require HPE-signed DIMMs and may be unavailable; Advanced ECC, mirroring, and online spare operate normally. Mixing NEMIX RAM with HPE-branded modules of the same spec in one server is supported. Every module carries a lifetime replacement warranty with free US-based technical support.

Ordering for fleets

NEMIX RAM is a registered federal supplier (UEI GV8MMYNDJ5J1, CAGE 59AB2) and accepts purchase orders with net terms for business, government, and education buyers. For multi-node, Synergy frame, or Apollo chassis upgrades, send the HPE quote in -B21 numbers, the OneView memory export, or the model and generation with node count, and we return the full set matched and shipped together. Volume and reseller pricing is available on request.

Frequently asked

Gen10 or Gen10 Plus — does it matter? Yes. Gen10 is DDR4-2666/2933 on 6 channels; Gen10 Plus and Gen10 Plus v2 are DDR4-3200 on 8 channels. Same model number, different memory. The generation is on the bezel; filter by it.

Will HPE support the server with third-party memory? The server warranty and support contract remain in force. HPE may decline to troubleshoot issues it attributes to non-HPE DIMMs and may ask you to remove them while diagnosing an unrelated fault; our lifetime warranty and support cover the modules.

My -B21 number is not on this page. HPE issues several -B21 numbers for the same spec across DRAM vendors and generations. Filter by capacity, rank, speed, and module type from the QuickSpecs line, or send us the number and we will match it.

Can the MicroServer or DL20 take SmartMemory RDIMM? No. Those boards are unbuffered-only. Use the ECC UDIMM listed for them.

Does Gen11 take LRDIMM? No. DDR5 generations are RDIMM-only; high capacities use 128GB and 256GB RDIMMs.